Ampthill is a town and civil parish in the Central Bedfordshire district of Bedfordshire, England. It lies between Bedford and Luton. At the 202…Ampthill is a town and civil parish in the Central Bedfordshire district of Bedfordshire, England. It lies between Bedford and Luton. At the 2021 census it had a population of 8,825. The name 'Ampthill' is of Anglo-Saxon origin. The first settlement was called 'Æmethyll', which literally means either 'anthill' or 'ant-infested hill'. In the Domesday Book, Ampthill is referred to as 'Ammetelle', with the landholder in 1086 being Nigel de la Vast. The actual entry reads: Ammetelle: Nigel de la Vast from Nigel d'Aubigny. A further variation may be 'Hampthull', in 1381.