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Merck, Keytruda and colorectal cancer
Merck's colorectal cancer therapy fails late-stage trial
Merck said on Wednesday a combination of its experimental drug and blockbuster therapy Keytruda failed a late-stage trial testing it in previously treated patients with a type of colorectal cancer. Th
Merck's Experimental Favezelimab/Keytruda Combo Fails In Late-Stage Colorectal Cancer Study
Merck & Co Inc (NYSE:MRK) released topline data from the KEYFORM-007 Phase 3 study of the fixed-dose combination of favezelimab and pembrolizumab versus the standard of care for pretreated patients with microsatellite-stable (MSS) metastatic colorectal cancer (mCRC).
Merck's Keytruda-LAG-3 combo fails to tame tough colorectal cancer in phase 3
An attempt by Merck & Co. to unlock the microsatellite stable (MSS) metastatic colorectal cancer market has ended in failure. | An attempt by Merck & Co. to unlock the microsatellite stable metastatic colorectal cancer market has ended in failure.
Merck’s Keytruda Combo Fails in Phase III Colorectal Cancer Study
Merck follows in the footsteps of Bristol Myers Squibb, which in December 2023 also failed to secure a late-stage victory for its combo regimen of a PD-1 blocker and an anti-LAG-3 antibody.
MRK's Keytruda Combo Fails in Phase III Colorectal Cancer Study
Merck MRK announced data from the phase III KEYFORM-007 study, which evaluated a fixed-dose combination of its anti-LAG-3 antibody, favezelimab and its blockbuster anti-PD-1 therapy, Keytruda in pre-treated patients with PD-L1 positive microsatellite stable (MSS) metastatic colorectal cancer (mCRC).
News Medical
2h
Disruption of circadian clock linked to accelerated colorectal cancer progression
Research from the University of California, Irvine has revealed how disruption of the circadian clock, the body's internal, ...
7d
on MSN
OPINION: My husband died at 48 from colorectal cancer. FIT Test is a lifesaver for others
Many people are simply unaware of the existence of the FIT test or underestimate its importance in colorectal cancer ...
Hosted on MSN
1d
New Research Identifies 2 'Red Flag' Symptoms of Early-Onset Colorectal Cancer
A new study has identified two symptoms that occur in nearly half of all people diagnosed with early-onset
colorectal
cancer
. Abdominal pain and blood in the stool were identified as symptoms ...
News Medical
2d
Stool-based testing offers a new hope for global colorectal cancer screening
"Stool-based test offers a promising solution to reduce the burden of a colonoscopy," experts emphasized on September 21st, ...
Armed robbery in Revesby
10h
Circadian Disruption, Gut Changes Tied to Colorectal Cancer
Research from the University of California, Irvine has revealed how disruption of the circadian clock, the body's ...
Medscape
3d
Sex and Gender Influence Outcomes in Colorectal Cancer
Factors related to sex and gender can affect therapy outcomes and should not be overlooked in clinical practice or research.
Cancer Therapy Advisor
1d
Postoperative Antibiotic Use May Worsen Colorectal Cancer Outcomes
Researchers sought to determine the effect of antibiotics on the risk of colorectal cancer recurrence after surgery.
C&EN
11d
Are Alzheimer’s disease and colorectal cancer inversely related?
Researchers also noticed that the mice used as models for Alzheimer’s disease who were given stool transplants from healthy ...
tyla
18h
Doctor shares 6 common signs of colon cancer in young people
Symptoms of anaemia include fatigue, cold hands and feet, hair loss, brittle nails, cognitive issues like brain fog, ...
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Merck
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