It's unclear who the immediate starter is over Mixon, so the Rams will likely see some combination of Dameon Pierce, Dare Ogunbowale, ex-Cleveland Browns running back Nick Chubb and fourth-round rookie Woody Marks. Chubb is listed as the team's second running back, but all four players have seen action in training camp and in the preseason.

The Los Angeles Rams will be somewhat familiar with their week one opponent, the Houston Texans. The Texans, coached by former San Francisco 49ers defensive coordinator DeMeco Ryans, hired former Rams tight ends coach Nick Caley to reinvent their offense around quarterback C.J. Stround.

Breaking: The Texans are not activating RB Joe Mixon by Tuesday’s 4 pm ET deadline, sources tell @AdamSchefter. This makes him ineligible to play at least the first four games this season due to an ankle injury and he will be moved to Reserve/Non-Football Injury, which… pic.twitter.com/5AMxHVCbKo

Cleveland Browns quarterback Shedeur Sanders said he expected to make the final 53-man roster despite struggling in the final preseason game of the year.

It's the Browns vs. Rams in Week 3 of the NFL preseason. Joe Flacco leads Cleveland into their only home game of the exhibition season.