Heme catabolism (from the breakdown of red cells) leads to the formation of the pigment bilirubin as an end product. About 80% of heme comes from the degradation of circulating erythrocytes; the ...

In July 2003, the National Institute of Child Health and Human Development (NICHD) organized a consensus conference, where a group of experts were invited to review and discuss the current state of ...

Breastfeeding jaundice occurs on the 2nd or 3rd day of life and results from insufficient milk intake due to inadequate production or poor breastfeeding technique. Shorter hospital stays result in ...

In studies in mice, researchers report they have found that bilirubin, a bile pigment most commonly known for yellowing the skin of people with jaundice, may play an unexpected role in protecting ...

A research team has investigated biliverdin reductase, the enzyme producing bilirubin -- a substance linked with jaundice -- from biliverdin (BV). Two BV molecules were found at the enzyme reaction ...

Low levels of bilirubin lead to more chances of brain damage, suggesting that bilirubin protects brain cells from superoxide reactions. In studies in mice, Johns Hopkins Medicine researchers report ...

Bilirubin, the primary breakdown product of hemoproteins, particularly hemoglobin, plays a key role in the diagnosis, prognosis, and monitoring of liver diseases. In acute liver diseases, such as ...

Medically reviewed by Kumkum S. Patel, MD Key Takeaways Jaundice is a common sign of liver failure caused by a buildup of bilirubin.Liver failure can cause confusion and neurological issues, including ...

In studies in mice, Johns Hopkins Medicine researchers report they have found that bilirubin, a bile pigment most commonly known for yellowing the skin of people with jaundice, may play an unexpected ...