The latest short science news items from C&EN. Open an introductory chemistry textbook. What is a covalent bond? A covalent bond occurs when atoms share electrons in a molecule. What is a hydrogen ...
Although small molecules can be excellent at finding and binding deep pockets on proteins of interest, many therapeutic targets with smooth surfaces remain hard to get a good handle on. Partly as a ...
Covalent drugs, largely ignored for decades, are staging a comeback. Five irreversible covalent kinase inhibitors have advanced to phase 3 in recent years, with Boehringer Ingelheim's afatinib now ...
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