Cyclophosphamide is widely used to treat severe manifestations of numerous autoimmune rheumatic diseases including systemic sclerosis. Based on recent data, immunological and inflammatory activation ...

Patients who underwent autologous stem cell transplantation (ASCT) for diffuse cutaneous systemic sclerosis (dcSSc), also known as scleroderma, did no better than others receiving conventional ...

Please provide your email address to receive an email when new articles are posted on . CHICAGO — A long-term follow-up to the Scleroderma: Cyclophosphamide or Transplantation trial demonstrated that ...

New clinical trial findings show that a therapeutic regimen involving transplantation of a person's own blood-forming stem cells can improve survival and quality of life for people with severe ...

An anti-cancer drug that suppresses the immune system is the first drug that has been shown to alleviate the most devastating effects of scleroderma, a disease of the connective tissues and lungs.

SAN DIEGO-A drug that suppresses the immune system and reduces inflammation has been shown to be effective in treating lung disease associated with the devastating connective tissue disease ...

Please provide your email address to receive an email when new articles are posted on . Myeloablative autologous stem cell transplantation improved long-term clinical outcomes, including overall ...

The approach could represent the first new treatment to improve survival in patients with severe scleroderma in more than four decades. An unusual autoimmune disease that causes skin and lung damage ...

Scleroderma with internal organ involvement is a debilitating and lethal autoimmune disorder with few effective treatments. But a study has now found new cause for optimism using an aggressive stem ...

First Bari Martz’s fingers turned blue. Then she started gasping for breath, and her joints stiffened so that she couldn’t even open her hands. Subscribe to read this story ad-free Get unlimited ...

Cyclophosphamide is well established as a potential treatment for severe manifestations of SSc. Recent data point towards limited efficacy in SSc-ILD with positive outcomes in lung function, ...