Comparison of two H3K4me3 antibodies using the SNAP-ChIP™ K-MetStat Panel. Blue bars quantify the relative recovery of each unique lysine-methylated nucleosome using qPCR.

In addition to anti-H3K9me3 antibodies, we developed anti-H3K4me3 antibodies. One clone, named 304M3-A, exhibited a K D value of 16 nM to H3K4me3 with high specificity and no substantial lot-to ...

MLL-r AML cells exhibit high levels of histone H3 lysine 4 trimethylation (H3K4me3), ... Scaling B-cell cloning workflows for antibody development. Matthieu Bennet & Dustin Whitson.

Chemical modifications such as H3K4me3 (tri-methylation of histone H3 lysine 4) can turn genes on or off, and are often altered in cancer. Using mouse stem cells, researchers were able to achieve ...