When a newborn is unable to pass stool, the cause could be Hirschsprung’s Disease, a rare congenital disorder that can lead to serious complications. Dr. Michael Rollins explains the disease and how ...

A manometric technic is described for the diagnosis of Hirschsprung's disease without the necessity of deep-muscle rectal biopsy. Separate pressure recordings were obtained from the internal and ...

Assembled Multipurpose Instrument for Rectal Biopsies (A) and Actual Size of the Biopsy Capsule (B), Which Has Been Removed to Show the Knife Attached to the Pull Wire. Three to 5 biopsies are ...

Scientists at the University of Michigan Medical School have identified defective stem cells as the key to a serious, sometimes life-threatening, intestinal disorder called Hirschsprung's disease, ...

FIGHTING TO GET BETTER TREATMENT OPTIONS FOR A RARE CHILDHOOD CONDITION. IT’S CALLED HIRSCHSPRUNG DISEASE. THE EARLIEST SIGN IN A NEWBORN IS OFTEN CONSTIPATION. THERE ARE TREATMENTS AVAILABLE. HERE’S ...

Hirschsprung disease is a congenital disorder clinically characterized by the absence of colonic ganglia and genetically by extensive heterogeneity. Genes involved include RET, GDNF, EDNRB and EDN3.

Caused by a congenital absence of innervation at the end of the bowel, Hirschsprung’s disease (HD) results in functional obstruction of the gut. The rectum and sigmoid colon are typically affected, ...

For many patients with Hirschsprung disease, the underlying pathogenic mechanisms are unknown. A new study using a novel line of transgenic mice and tissue from patients with Hirschsprung disease ...

Ankush Gosain, MD, PhD, of Le Bonheur Children's Hospital and the University of Tennessee Health Science Center has focused his research on determining the mechanisms underlying abnormal development ...

A UK collaboration is advancing a first-in-class regenerative, stem cell therapy for Hirschsprung disease to reshape ...

MONTREAL--(BUSINESS WIRE)--Neurenati Therapeutics Inc., a biotech company focused on rare pediatric diseases, is pleased to announce that the U.S. Food and Drug Administration (FDA) has granted both ...

Last week news broke of a 22-year-old man in China who had a large section of his colon removed. The man, Zhou Hai, had been constipated for a number of months. After seeking medical help for ...