Chromatography remains a cornerstone in the purification of proteins, offering a suite of techniques that separate components based on differential interactions with a mobile phase and a stationary ...

Depending on the process and who provides the statistics, downstream processing accounts for between 50–80% of the cost of producing biotech drugs. Whatever the exact number, protein purification ...

Three-phase partitioning (TPP) is an efficient and cost-effective method for protein purification that exploits the simultaneous addition of salts and organic solvents to an aqueous protein extract.

Cytiva introduced a new technology called Protein Select that the company says is designed to streamline and accelerate recombinant protein purification. The self-cleaving traceless tag and ...

There are a wide variety of protein-based drugs that are used to treat various serious conditions. Insulin is perhaps the most well-known example, which is used for life-saving treatments for diabetes ...

Conventionally, chromatography is used for protein purification, which is extremely expensive. Alternatively, the protein crystallization method could be used to determine protein structure, but this ...

Engineers devised a way to purify protein drugs during manufacturing. Their approach, which uses nanoparticles to rapidly crystallize proteins, could help make protein drugs more affordable and ...

Self-removing tags can be used for simple and effective purification of recombinant proteins and peptides. The key component of these tags is an intein, which is a protein element with the ability to ...

Centrifugation and filtration have been widely accepted as techniques required for clarifying complex cell cultures to recover extracellular proteins such as monoclonal antibodies (mAbs). However, ...

Protein samples are essential to advance our understanding of disease pathways and develop new therapeutics. High-quality filtration is needed to protect purity, yield and functionality of target ...

Stop relying on ultra-processed supplements and discover why dietitians recommend whole-food sources to build more muscle, ...

Real-time and in-line accurate measuring of protein (monoclonal antibody, or mAb) concentration has been shown across a wide dynamic range (0–135 g/L) through the ...