Researchers show benefit of ultra-deep RNA sequencing in Mendelian disorder diagnostics

RNA sequencing (RNA-seq) is a powerful tool in diagnosing Mendelian disorders, but the optimized sequencing depth for this ...
HealthTech

Perturb-Seq in Practice: Dissecting Gene Function with CRISPR + scRNA-Seq

In modern functional genomics, understanding how specific genes control cellular behavior requires both targeted intervention and high-resolution analysis. That’s where Perturb-Seq comes in—a method ...
Hosted on MSN

Single-cell RNA sequencing of bone metastases from multiple cancer types reveals three distinct immune archetypes

Bone is a common site for metastasis of solid cancers, but histological and molecular features of bone metastases are not well understood. In a new study published in Cell Genomics, researchers at ...
Baylor College of Medicine

Single-cell RNA sequencing of bone metastases reveals distinct immune archetypes

Bone is a common site for metastasis of solid cancers, but histological and molecular features of bone metastases are not well understood. In a new study published in Cell Genomics, researchers at ...