earning spatial elements of a new environment is important for people and animals. However, how this process occurs in the brain remains poorly understood. Long noncoding RNA (lncRNA) are abundantly ...

Researchers at Johns Hopkins Medicine, led by Bindu Paul, an associate professor of pharmacology, psychiatry and neuroscience ...

Researchers have identified a brain protein whose absence leads to memory loss and Alzheimer’s-like damage in mice.

We often think of memory as stable—a mental archive that stores experiences in neat, retrievable files. But what if those files quietly shift positions, even when the original experience hasn’t ...

A protein that produces hydrogen sulfide may be a new therapeutic target, as its deficiency is linked to cognitive deficits ...

Cystathionine γ-lyase shows promise as a protein target for Alzheimer's disease, potentially offering new pathways for ...

Scientists at Johns Hopkins Medicine say results of a new study are advancing efforts to exploit a new target for Alzheimer's disease: a protein that manufactures an important gas in the brain.

For decades, Alzheimer’s research has largely focused on slowing decline, not restoring what was lost. Now a series of animal studies suggests that resetting the brain’s energy metabolism can do ...

In the realm of memories, "where" holds special importance. Where did I leave my keys? Where did I eat dinner last night? Where did I first meet that friend? Recalling locations is necessary for daily ...

A groundbreaking study shows that two repurposed cancer drugs, when combined, can correct complex brain cell dysfunction and restore memory in Alzheimer’s mouse models, offering hope for new ...