Definition: The extracellular matrix is the non-cellular network of proteins and polysaccharides that surrounds cells, gives tissues mechanical structure, and provides biochemical and mechanical ...

A new review in Materials Today Bio argues that the age of the extracellular matrix is an overlooked variable in 3D cancer ...

Through an electron microscope they may look like the giant sandworms from Dune, but C. elegans nematodes are only 1 millimeter long. The worms have a layer that covers their bodies called the apical ...

(Eugene Mymrin/Moment RF/Getty Images) It's well known that alcohol has profound consequences on the way the brain works, and research shows that even low levels of the drug can damage your brain. But ...

A Cleveland Clinic research team studying alcohol and the brain discovered a new way that alcohol abuse can cause brain dysfunction and damage: through immune cells called microglia. The research also ...

Extracellular matrix engineering harnesses the structural and biochemical complexity of the native cellular microenvironment to direct cell adhesion, migration, proliferation and differentiation. By ...

Growing from a single cell into a complex organism with specialized tissues and organs requires a complex and coordinated process. But the mechanical signals that guide tissue and organ ...

A groundbreaking study led by Children's Hospital Los Angeles has found a novel mechanism behind neuroblastoma progression: the shape and structure of the extracellular matrix. The study, led by ...

A new mouse and human tissue study shows that the transcription factor Snai1 reprograms retinal pericytes to deposit and ...

The numerous cells that make up mammalian tissues are surrounded by an intricate network of proteins known as the extracellular matrix (ECM). Together, these proteins provide cells with a structural ...

Irritable bowel diseases are tireless cycles of recovery and remission, but what drives remission is still a mystery. In a new study published in Immunity, | Digestive System ...