A powerful Israeli air strike flattened a residential building in central Beirut early Saturday, killing at least 16 people and wounding 63 others, while a Hezbollah official denied it targeted a senior commander with the militant group.

Dozens of people have been killed by Israeli strikes in Lebanon, including 20 who died after a strike flattened a multi-story residential building in central Beirut overnight, according to Lebanese officials.

An Israeli airstrike killed at least 20 people in central Beirut on Saturday, Lebanon's health ministry said, one of the deadliest strikes on the heart of the capital since Israel began its assault against the Iran-backed Hezbollah group in September.