The San Francisco 49ers will be without their starting quarterback and their best defensive player when they visit the Green ...

The San Francisco 49ers fell to 5-6 on the season in losing to the Green Bay Packers on Sunday. Top takeaways with Brock ...

Jaire Alexander, Edgerrin Cooper, Brock Purdy and Nick Bosa were all ruled out Friday; 49ers LT Trent Williams joins them on ...

The San Francisco 49ers will be missing two of their best players in their must-win matchup against the Green Bay Packers ...

Kyle Shanahan made a stunning revelation involving the health of Nick Bosa following the loss to the Seahawks.

San Francisco 49ers star Nick Bosa admitted he drew inspiration from President-elect Donald Trump with his sack celebration ...

The San Francisco 49ers are expecting to get star tight end George Kittle back this week for a key game against Green Bay, ...

San Francisco 49ers head coach Kyle Shanahan has offered an update on the injuries to Nick Bosa and Brock Purdy.

San Francisco 49ers tight end George Kittle confidently declared on Wednesday that he will suit up for this weekend's game ...

The 49ers have allowed 222 points, or 22.2 points per game, tied for 16th. Last year, the defense allowed 298 points, or 17.5 ...

San Francisco 49ers star defensive end Nick Bosa provided an injury update that could end up ruining their season.

Brandon Allen will start in place of an injured Brock Purdy when the 49ers (5-5) also have to play without Nick Bosa on ...