Yemen’s Houthi rebels are stepping up their missile attacks, keeping up what could be the last major front in the Middle East wars.

Air raid sirens rung out in Jerusalem after a missile was launched from Yemen towards Israel, according to the Israeli military. (AP video by Yesica Fisch and Sam Mednick)

The latest round of strikes occurred as the United States and its ally Israel struggle to halt a campaign of regional assaults by Yemen’s Houthi militants.

The US military fired multiple strikes against the Houthi rebels in Yemen, the latest escalation against the Iran-backed terror group plaguing the Red Sea.

Israel is signaling a wider campaign against Houthi militants in Yemen, a mountainous and impoverished country more than 1,000 miles from Israeli territory.

The US military on Tuesday said it hit targets in Yemen targeting the Houthi militia, hours after the Iran-backed group launched attacks on Israel. The United States Central Command (CENTCOM) said its warships and aircraft attacked a number of Houthi-linked sites,

Israel has severely weakened Hamas and Hezbollah. Now it's going after another member of Iran's so-called axis of resistance: the Houthi rebels of Yemen.

The head of the World Health Organization said he was about to board a flight in the Yemeni capital when the airport came under bombardment.

As part of the expanded US strikes on Yemen, and amid increased Houthi attacks on Israel, the Americans will reportedly hit more missile-related targets.

Yemen’s Houthi rebels have fired hypersonic ballistic missile and drone towards the city of Yaffa near Tel Aviv, striking their intended target accurately, the group said Friday. The operations took place on Friday,

Gaza's civil defence agency said around 30 people were killed in Israeli bombardments on Friday, as Hamas said indirect negotiations for a truce in the war were set to resume in Qatar later.The Israeli military said three rockets targeted its territory from the Gaza Strip,