Deep in coastal mangroves and even inside our own mouths, biologists are finding that DNA does not always sit in a simple ...

Inside every human cell, six feet of DNA folds into a nucleus that is only a few micrometers wide, yet still manages to ...

Key PointsResearch on HIV's conical capsid that began over 25 years ago led to the development of lenacapavir, the world's ...

Age related decline in female fertility remains one of the most urgent challenges facing reproductive medicine today. The decline affects both the number and the quality of oocytes, which reduces chan ...

A recently recognized form of dementia is changing the understanding of cognitive decline, improving the ability to diagnose patients and ...

Scientists engineered stem cells with “interrupted” CAG repeats to break up the toxic stretch. This may stop expansion, and could improve problems in cells that model Huntington’s disease. This study ...

By setting up both reactions side by side in a test tube, the team revealed a literal tug-of-war between two DNA-repair pathways acting on the same HTT repeat. Which side wins likely determines ...

One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published ...

Although it also performs some functions in men, estrogen, the main female sex hormone, is involved in a myriad of processes, ...

A tiny percentage of our DNA—around 2%—contains 20,000-odd genes. The remaining 98%—long known as the non-coding genome, or ...

All year long, these moments captivated the public, demonstrated dangerous trends, and pushed research and innovation forward ...

Membraneless organelles, also called biomolecular condensates, are changing how scientists think about protein chemistry, ...