The high complexity and diversity of the eukaryotic transcriptome poses significant challenges for the efficient detection of specific transcripts. Conventional targeted RNA-seq methods often require ...

and REAP-seq (RNA expression and protein sequencing assay) to investigate the relationship between RNA transcripts and proteins, and identify new cell types and cell states associated with disease.

RNA sequencing (RNA-Seq) uses NGS to profile the transcriptome ... Techniques such as bisulfite sequencing (for DNA methylation) and ChIP-Seq (for histone modifications) have been developed to map ...

Oxford Nanopore Technologies observes that direct analysis has already enhanced research across species, disease states, and applications.

Next-generation sequencing (often noted as NGS), describes the high-throughput technologies that can now determine the sequence of a given nucleic acid strand, such as DNA or RNA, in a matter of hours ...

This application note explores an optimized RNA-sequencing workflow that reliably determines cell subset abundance and cell-type-specific gene expression profiles from bulk tissue or blood expression ...

The company can now sequence long strands of DNA/RNA molecules without ... Capturing mRNA on a chip and using spatial barcoding makes in situ sequencing possible, linking gene expression with ...

We aim to combine data from different sources, e.g, TF binding data (ChIP-seq and ChIP-chip), gene expression data (microarray and RNA-seq), with computational techniques to construct the integrated ...

Users can benefit from the reduced background inherent in ChIP technology, which performs faster and is considerably simpler to use than traditional kits.

We also offer RNA integrity, DNA fragment and sequencing library analysis using our Bioanalyser. Initially set up as an Affymetrix-accredited laboratory to run an Affymetrix Gene Chip Microarray ...

Our analysis of DNase-seq data in the T cell lineage and of Foxp3 ChIP-seq in regulatory T cells (Tregs ... We are now exploiting recent next-generation RNA sequencing technologies to map co- and post ...