The 49ers travel to Buffalo to take on the AFC East-leading Buffalo Bills. Check out our best bet for the game ...

If defense wins championships, NFL quarterbacks win headlines—and a whole lot of blame when things go south. Week 12 gave us ...

San Francisco 49ers quarterback and Iowa State alum Brock Purdy is showing promising signs after being injured on Nov. 17.

But even if the 49ers had the trio of stars, the game’s result likely would have stayed the same (although the score likely ...

San Francisco quarterback Brock Purdy took part in some light throwing on Monday after missing his first career game because ...

The Buffalo Bills' upcoming opponent, the San Francisco 49ers, provided a big injury update for their starting quarterback ...

San Francisco 49ers head coach Kyle Shanahan told reporters that quarterback Brock Purdy did some light throwing without any ...

Getting blown out in Green Bay following another squandered late lead the previous week against Seattle has quickly turned ...

The 49ers' PFF grades show there is plenty of blame to go around in San Francisco's embarrassing 38-10 loss to the Green Bay ...

Brandon Allen's first start with the 49ers didn't go so well. He made some nice throws, but he fumbled twice, threw an ...

The Packers blew out an undermanned 49ers squad on Sunday and these five players stood out for Green Bay in both positive and ...

Coach Kyle Shanahan said Purdy (shoulder) did some light throwing Monday and didn't have any issues, Nick Wagoner of ESPN.com reports. Purdy will rest Tuesday and see how the shoulder feels over the ...