The San Francisco 49ers will be without their starting quarterback and their best defensive player when they visit the Green ...

The San Francisco 49ers will be missing two of their best players in their must-win matchup against the Green Bay Packers ...

San Francisco 49ers star edge rusher Nick Bosa left Sunday's game with an injury before the Seahawks rallied to win the NFC ...

This just isn't the 49ers' week. They have now been dealt the worst-case scenario with Nick Bosa's status against the Packers ...

The 49ers have allowed 222 points, or 22.2 points per game, tied for 16th. Last year, the defense allowed 298 points, or 17.5 ...

San Francisco 49ers quarterback Brock Purdy will miss Sunday's game against the Green Bay Packers with a sore throwing ...

Brandon Allen will start in place of an injured Brock Purdy when the 49ers (5-5) also have to play without Nick Bosa on ...

The San Francisco 49ers are expecting to get star tight end George Kittle back this week for a key game against Green Bay, ...

While the status of quarterback Brock Purdy has dominated headlines, injuries to tackle Trent Williams and defensive end Nick ...

Brock Purdy and Nick Bosa are not available for the San Francisco 49ers when they enter Green Bay with designs on finding ...

The Seattle Seahawks' arch rivals, the San Francisco 49ers, did not just lose a game last week. Their 20-17 defeat proved to ...

Big news and not good news out of the Bay Area on Friday. The 5-5 San Francisco 49ers will be in Green Bay on Sunday to play ...