The 49ers on Monday night did what they had to do to keep their hopes of the No. 1 seed alive.The offense did most of the ...

The 49ers just beat the Indianapolis Colts 48-27 and won their 11th game of the season. Last season, they lost 11 games.

Purdy is the first Niners quarterback to throw five touchdown passes in a game since Steve..

San Francisco 49ers head coach Kyle Shanahan talks to the media after Week 16 win against the Indianapolis Colts about goals ...

Highlights from the Week 16 matchup between the San Francisco 49ers and the Indianapolis Colts during the 2025 ...

Watch the best plays by the San Francisco 49ers against the Indianapolis Colts in Week 16 of the 2025 NFL..

Brock Purdy and the 49ers turned it up a notch against the Colts to close out Week 16, despite having already clinched a ...

The San Francisco 49ers finished their Week 16 "Monday Night Football" contest with a 48-27 win over the Indianapolis Colts ...

The 49ers had three players deal with injuries on Monday night against the Colts. Here's what Kyle Shanahan said about ...

Things didn't start out too well for the 49ers defense in their 48-27 win over the Indianapolis Colts on Monday night, but by the time the game was ...

Newly unretired Philip Rivers turned in an impressive individual performance Monday night that saw him throw for 277 yards and two touchdowns. But it ...

San Francisco 49ers kicker Eddy Piñeiro makes a 38-yard field..