Comparison of two H3K4me3 antibodies using the SNAP-ChIP™ K-MetStat Panel. Blue bars quantify the relative recovery of each unique lysine-methylated nucleosome using qPCR.

The results demonstrate that H3K4me3 is involved in stabilizing chromosomes and spindles, and is crucial for normal oocyte development and subsequent embryogenic potential. "We are very encouraged ...

Chemical modifications such as H3K4me3 (tri-methylation of histone H3 lysine 4) can turn genes on or off, and are often altered in cancer. Using mouse stem cells, researchers were able to achieve ...