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The AFC East-leading Buffalo Bills return from their bye week to host the inconsistent San Francisco 49ers on Sunday night.

Christian McCaffrey and the 49ers travel to Buffalo to take on Josh Allen and the Bills for Sunday Night Football. Live ...

There may be some justice for a young Packers fan who was denied an autographed football he won this weekend at a 49ers ...

Renee Miller equates players to Thanksgiving foods — savory or unsavory — to help you get set for the holiday weekend.

Olivia Culpo tells PEOPLE exclusively how she plans to spend the holidays with Christian McCaffrey for the first time since ...

Since returning to the field, McCaffrey has recorded 149 yards on the ground on 43 attempts for 3.5 yards per attempt. In the ...

Saquon Barkley has become the Shohei Ohtani of the NFL. There’s no better home run hitter playing football right now. Barkley ...

On Monday, San Francisco 49ers head coach Kyle Shanahan addressed wide receiver Deebo Samuel's underwhelming performances ...

San Francisco has put up a combined 27 points the past two weeks and faces a Bills defense great at generating pressure with ...

Injured starters Brock Purdy, Trent Williams and Nick Bosa are all captains. So are George Kittle, Christian McCaffrey, Kyle Juszczyk, Deebo Samuel and Fred Warner. Kittle is the only one who ...

If we've learned anything about the San Francisco 49ers brain trust this season, we can't take what they say at face value. After all, we saw 49ers star running ...