Ever since making the switch from high school receiver to running back in college, Isaac Guerendo has had few opportunities ...

The 49ers just lost 35-10 to the Buffalo Bills. Now the 49ers are 5-7 and all alone in last place in the NFL West. Here are ...

Josh Allen expertly navigated snow-topped turf, finding the end zone in a multitude of fashions and even receiving credit for ...

The 49ers (5-7) are alone in last place in the NFC West for the first time since the 2020 season ended. On the heels of this ...

Before the 2024 NFL season, Sunday night's Week 13 matchup between the Buffalo Bills and San Francisco 49ers might've been ...

The Bills are a Super Bowl contender and the 49ers somehow probably aren’t even a playoff team. That’s how Sunday night’s ...

The Buffalo Bills dominated the San Francisco 49ers on Sunday night, winning 35-10 in Highmark Stadium in Orchard Park, N.Y.

San Francisco 49ers star running back Christian McCaffrey will not need surgery on his injured right knee but will miss the ...

McCaffrey slid down untouched in the backfield after taking a toss, then immediately went to the 49ers’ medical tent and ...

NFL Week 14 odds, picks, predictions, TV channel, streaming information for Sunday football game between Chicago Bears and ...

Christian McCaffrey is dealing with an injury again. The 49ers running back went down with a knee injury in the second ...

It's Buffalo Bills vs San Francisco 49ers in Week 13 of the NFL season. Can Josh Allen and company outduel Christian ...